Clinical and microbiological diagnosis of oral candidiasis

Clinical and microbiological diagnosis of oral candidiasis

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Clinical and microbiological diagnosis of oral candidiasis

Show simple item record Coronado Castellote, Laura es Jiménez Soriano, Yolanda es 2014-05-22T09:42:29Z 2014-05-22T09:42:29Z 2013 es
dc.identifier.citation Coronado Castellote, Laura ; Jiménez Soriano, Yolanda. Clinical and microbiological diagnosis of oral candidiasis. En: Journal of Clinical and Experimental Dentistry, 2013, Vol. 5, No. 5: 279-286 es
dc.description.abstract Introduction: Candidiasis or oral candidiasis is the most frequent mucocutaneous mycosis of the oral cavity. It is produced by the genus Candida, which is found in the oral cavity of 53% of the general population as a common commensal organism. One hundred and fifty species have been isolated in the oral cavity, and 80% of the isolates correspond to Candida albicans, which can colonize the oral cavity alone or in combination with other species. Transformation from commensal organism to pathogen depends on the intervention of different predisposing factors that modify the microenvironment of the oral cavity and favor the appearance of opportunistic infection. The present study offers a literature review on the diagnosis of oral candidiasis, with the purpose of establishing when complementary microbiological techniques for the diagnosis of oral candidiasis should be used, and which techniques are most commonly employed in routine clinical practice in order to establish a definitive diagnosis. Materials and methods: A Medline-PubMed, Scopus and Cochrane search was made covering the last 10 years. Results: The diagnosis of oral candidiasis is fundamentally clinical. Microbiological techniques are used when the clinical diagnosis needs to be confirmed, for establishing a differential diagnosis with other diseases, and in cases characterized by resistance to antifungal drugs. Biopsies in turn are indicated in patients with hyperplastic candidiasis. Staining (10% KOH) and culture (Sabouraud dextrose agar) are the methods most commonly used for diagnosing primary candidiasis. Identification of the individual species of Candida is usually carried out with CHROMagar Candida®. For the diagnosis of invasive candidiasis, and in cases requiring differentiation between C. albicans and C. dubliniensis, use is made of immunological and genetic techniques such as ELISA and PCR. en_US
dc.subject Odontología es
dc.subject Ciencias de la salud es
dc.title Clinical and microbiological diagnosis of oral candidiasis es
dc.type journal article es_ES
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.type.hasVersion VoR es_ES

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